Desmocollin 2 antibody [C1C2], Internal

GeneTex

Desmocollin 2 antibody [C1C2], Internal

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

DSC2

desmocollin 2

ARVD11; cadherin family member 2; CDHF2; desmocollin-2; desmosomal glycoprotein II/III; DG2; DGII/III; DSC3

Rabbit

IgG

Desmocollin-2

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203