Desmocollin 2 antibody [HL3572]

GeneTex

Desmocollin 2 antibody [HL3572]

9

This antibody was raised against human Desmocollin 2 Intracellular domain.

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL3572

1 mg/ml

Unconjugated

DSC2

desmocollin 2

ARVD11; cadherin family member 2; CDHF2; desmocollin-2; desmosomal glycoprotein II/III; DG2; DGII/III; DSC3

Rabbit

IgG

Desmocollin-2

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203