Bio-Connect
IHC-P analysis of human skin tissue using GTX34676 Desmoglein 3 antibody [5G11].
IHC-P analysis of human skin tissue using GTX34676 Desmoglein 3 antibody [5G11].
IHC-P analysis of human skin tissue using GTX34676 Desmoglein 3 antibody [5G11].

Desmoglein 3 antibody [5G11]

GTX34676
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetDSG3
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Desmoglein 3 antibody [5G11]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family.
  • Application Supplier Note
    WB: 1-2microg/ml. ICC/IF: 1-2microg/ml. IHC-P: 1-2microg/ml for 30 minutes at RT. FACS: 1-2microg/106 cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    5G11
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1830
  • Target name
    DSG3
  • Target description
    desmoglein 3
  • Target synonyms
    130 kDa pemphigus vulgaris antigen; ABOLM; cadherin family member 6; CDHF6; desmoglein-3; PVA
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP32926
  • Protein Name
    Desmoglein-3
  • Scientific Description
    This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Nisin, a food preservative produced by Lactococcus lactis, affects the localization pattern of intermediate filament protein in HaCaT cells.
    Read more
  • Inhibition of JNK in HaCaT cells induced tight junction formation with decreased expression of cytokeratin 5, cytokeratin 17 and desmoglein 3.
    Read more