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Destruxin B

HY-N6690
MedChem Express
CAS Number2503-26-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.86
Molecular Weight621.81
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Destruxin B [2503-26-6]
  • Delivery Days Customer
    9
  • CAS Number
    2503-26-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.86
  • Molecular Formula
    C32H55N5O7
  • Molecular Weight
    621.81
  • Scientific Description
    Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells[1]. Destruxin B significantly activates caspase-3 and reduces tumor cell proliferation through caspase-mediated apoptosis, not only in vitro but also in vivo[2].
  • SMILES
    O=C(N[C@]([C@@H](C)CC)(C)C(N(C)[C@@H](C(C)C)C(N(C)[C@@H](C)C(NCC1)=O)=O)=O)[C@@](CCC2)(C)N2C([C@@H](CC(C)C)OC1=O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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