Destruxin B [2503-26-6]

TargetMol Chemicals

Destruxin B

44

2503-26-6

Chemical

Research Use Only

Destruxin B

C30H51N5O7

593.766

Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Metarhizium isopliae. Destruxin B induces apoptosis of human non-small cell lung cancer cells through the Bcl-2 family-dependent mitochondrial pathway. Destruxin B through caspase-mediated apoptosis can significantly activate caspase-3 in vitro and in vivo, reducing the proliferation of tumor cells.

3 years

CC[C@H](C)[C@]1(C)NC(=O)[C@]2(C)CCCN2C(=O)[C@@H](CC(C)C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C1=O

-20°C

12352200