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Deucravacitinib

HY-117287
MedChem Express
CAS Number1609392-27-9
DownloadMSDS
Product group Chemicals
Estimated Purity99.87
Molecular Weight425.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Deucravacitinib [1609392-27-9]
  • Delivery Days Customer
    10
  • CAS Number
    1609392-27-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.87
  • Molecular Formula
    C20H19D3N8O3
  • Molecular Weight
    425.46
  • Scientific Description
    Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain ( IC 50 =1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways. Deucravacitinib, the FDAs world first de novo deuterium, is available for study in moderate to severe plaque psoriasis [1] [2] .
  • SMILES
    O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200