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Deucravacitinib (BMS-986165)

M4138
AbMole BioScience
CAS Number1609392-27-9
Product group Chemicals
Molecular Weight425.46
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Deucravacitinib (BMS-986165)
  • Delivery Days Customer
    9
  • CAS Number
    1609392-27-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C20H19D3N8O3
  • Molecular Weight
    425.46
  • Scientific Description
    Deucravacitinib (BMS-986165) is a first-in-class, selective, orally bioavailable inhibitor of TYK2 transitions.Deucravacitinib selectively binds the TYK2 pseudokinase (JH2) structural domain with an IC50 of 1.0 nM and a Ki value of 0.02 nM. Deucravacitinib (BMS-986165) blocks receptor-mediated Tyk2 activation by stably regulating the JH2 structural domain. deucravacitinib also inhibits the IL-12/23 and type I IFN pathways. deucravacitinib may be used in psoriasis research.
  • SMILES
    C(NC(=O)C1=C(NC2=CC=CC(=C2OC)C3=N[N](C)C=N3)C=C(NC(=O)C4CC4)N=N1)([2H])([2H])[2H]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200