IHC-P analysis of human breast carcinoma using GTX81693 DFNA5 antibody, N-term.
IHC-P analysis of human breast carcinoma using GTX81693 DFNA5 antibody, N-term.
DFNA5 antibody, N-term
GTX81693
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGSDME
Overview
- SupplierGeneTex
- Product NameDFNA5 antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. IHC-P: 1:50-1:100. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1687
- Target nameGSDME
- Target descriptiongasdermin E
- Target synonymsDFNA5, ICERE-1, gasdermin-E, DFNA5, deafness associated tumor suppressor, inversely correlated with estrogen receptor expression 1, non-syndromic hearing impairment protein 5, nonsyndromic hearing impairment protein
- HostRabbit
- IsotypeIgG
- Protein IDO60443
- Protein NameGasdermin-E
- Scientific DescriptionHearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Lv J, Liu Y, Mo S, et al. Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Nat Cell Biol. 2022,24(3):364-372. doi: 10.1038/s41556-022-00857-4Read this paper
Datasheet
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