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DIAPH3 antibody [C1C3]

GTX102892
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetDIAPH3
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Overview

  • Supplier
    GeneTex
  • Product Name
    DIAPH3 antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID81624
  • Target name
    DIAPH3
  • Target description
    diaphanous related formin 3
  • Target synonyms
    AN; AUNA1; DIA2; diap3; diaphanous homolog 3; DRF3; mDia2; NSDAN; protein diaphanous homolog 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NSV4
  • Protein Name
    Protein diaphanous homolog 3
  • Scientific Description
    Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Novel stromal biomarker screening in pancreatic cancer patients using the in vitro cancer-stromal interaction model. Nishida Y et al., 2020 Dec 9, BMC Gastroenterol
    Read more

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