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The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA033015(DIO2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: X200)
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA033015(DIO2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: X200)
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA033015(DIO2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: X200)

DIO2 Antibody

CSB-PA033015
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDIO2
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Overview

  • Supplier
    Cusabio
  • Product Name
    DIO2 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1734
  • Target name
    DIO2
  • Target description
    iodothyronine deiodinase 2
  • Target synonyms
    5DII, D2, DIOII, SELENOY, SelY, TXDI2, type II iodothyronine deiodinase, deiodinase, iodothyronine type II, deiodinase-2, deiodonase-2, selenoprotein Y, thyroxine deiodinase, type II, type 2 DI, type 2 iodothyronine deiodinase, type-II 5'-deiodinase, type-II 5'deiodinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92813
  • Protein Name
    Type II iodothyronine deiodinase
  • Scientific Description
    The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3,5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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