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Western Blot Positive WB detected in: 293 whole cell lysate All lanes: DKK1 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 29 kDa Observed band size: 38 kDa
Western Blot Positive WB detected in: 293 whole cell lysate All lanes: DKK1 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 29 kDa Observed band size: 38 kDa
Western Blot Positive WB detected in: 293 whole cell lysate All lanes: DKK1 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 29 kDa Observed band size: 38 kDa

DKK1 Recombinant Monoclonal Antibody

CSB-RA576260A0HU
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetDKK1
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Overview

  • Supplier
    Cusabio
  • Product Name
    DKK1 Recombinant Monoclonal Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1D12
  • Conjugate
    Unconjugated
  • Gene ID22943
  • Target name
    DKK1
  • Target description
    dickkopf Wnt signaling pathway inhibitor 1
  • Target synonyms
    DKK-1, SK, dickkopf-related protein 1, dickkopf 1 homolog, dickkopf-1 like, dickkopf-like protein 1
  • Isotype
    IgG
  • Protein IDO94907
  • Protein Name
    Dickkopf-related protein 1
  • Scientific Description
    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (PubMed:17143291). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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