DMOG

MedChem Express

DMOG [89464-63-1]

10

89464-63-1

Research Use Only

99.77

C6H9NO5

175.14

DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1alpha stabilisation and accmulation?in vitro and in vivo[1]. DMOG is an alpha-ketoglutarate analogue and inhibits alpha-KG-dependent hydroxylases. DMOG?acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal[2][4]. DMOG induces cell autophagy[5].

O=C(OC)CNC(C(OC)=O)=O

-20°C,2°C to 8°C

12352200