DMOG
HY-15893
Overview
- SupplierMedChem Express
- Product NameDMOG [89464-63-1]
- Delivery Days Customer10
- CAS Number89464-63-1
- CertificationResearch Use Only
- Estimated Purity99.77
- Molecular FormulaC6H9NO5
- Molecular Weight175.14
- Scientific DescriptionDMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1alpha stabilisation and accmulation in vitro and in vivo[1]. DMOG is an alpha-ketoglutarate analogue and inhibits alpha-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal[2][4]. DMOG induces cell autophagy[5].
- SMILESO=C(OC)CNC(C(OC)=O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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Product group Chemicals
CAS Number89464-63-1
Molecular Weight175.14 g/mol
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