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DMOG

M2558
AbMole BioScience
CAS Number89464-63-1
DownloadDatasheet
Product group Chemicals
Estimated Purity>99%
Molecular Weight175.14
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    DMOG
  • Delivery Days Customer
    9
  • CAS Number
    89464-63-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Molecular Formula
    C6H9NO5
  • Molecular Weight
    175.14
  • Scientific Description
    DMOG (Dimethyloxaloyl glycine) is an antagonist of alfa-ketoglutarate cofactor and a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1alfa stabilisation and accmulation in vitro and in vivo. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.
  • SMILES
    COC(=O)CNC(=O)C(=O)OC
  • UNSPSC
    12352200