DNA ligase I antibody [10H5]
GTX70141
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetLIG1
Overview
- SupplierGeneTex
- Product NameDNA ligase I antibody [10H5]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10H5
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID3978
- Target nameLIG1
- Target descriptionDNA ligase 1
- Target synonymsIMD96, LIGI, hLig1, DNA ligase 1, ligase I, DNA, ATP-dependent, polydeoxyribonucleotide synthase [ATP] 1
- HostMouse
- IsotypeIgG1
- Protein IDP18858
- Protein NameDNA ligase 1
- Scientific DescriptionThis gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wei L, Ploss A. Hepatitis B virus cccDNA is formed through distinct repair processes of each strand. Nat Commun. 2021,12(1):1591. doi: 10.1038/s41467-021-21850-9Read this paper
- Wei L, Ploss A. Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation. Nat Microbiol. 2020,5(5):715-726. doi: 10.1038/s41564-020-0678-0Read this paper
- Tsai YC, Wang YH, Liu YC. Overexpression of PCNA Attenuates Oxidative Stress-Caused Delay of Gap-Filling during Repair of UV-Induced DNA Damage. J Nucleic Acids. 2017,2017:8154646. doi: 10.1155/2017/8154646Read this paper
- Yuan Y, Britton S, Delteil C, et al. Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein. Nucleic Acids Res. 2015,43(21):10264-76. doi: 10.1093/nar/gkv894Read this paper
- Horton JK, Stefanick DF, Gassman NR, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013,12(9):774-85. doi: 10.1016/j.dnarep.2013.06.004Read this paper
- Masaoka A, Gassman NR, Horton JK, et al. Interaction between DNA Polymerase β and BRCA1. PLoS One. 2013,8(6):e66801. doi: 10.1371/journal.pone.0066801Read this paper
- Prasad R, Williams JG, Hou EW, et al. Pol β associated complex and base excision repair factors in mouse fibroblasts. Nucleic Acids Res. 2012,40(22):11571-82. doi: 10.1093/nar/gks898Read this paper
- Asagoshi K, Liu Y, Masaoka A, et al. DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst). 2010,9(2):109-19. doi: 10.1016/j.dnarep.2009.11.002Read this paper
- Guo Z, Zheng L, Dai H, et al. Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Nucleic Acids Res. 2009,37(10):3431-41. doi: 10.1093/nar/gkp201Read this paper
- Song W, Levin DS, Varkey J, et al. A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. J Biol Chem. 2007,282(31):22721-30.Read this paper
Datasheet
Related products
Product group Antibodies
DNA Ligase 1 Recombinant Antibody, AbBy Fluor-405 ConjugatedBSM-61877R-BF405
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
TargetLIG1
- SizePrice
Product group Antibodies
ApplicationsImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetLIG1
- SizePrice
Product group Antibodies
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
- SizePrice
Product group Antibodies
Anti-LIG1 Antibody144-01858
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
TargetLIG1
- SizePrice
Product group Antibodies
ApplicationsWestern Blot, ELISA
TargetLIG1
- SizePrice
Product group Antibodies
ApplicationsWestern Blot
TargetLIG1
- SizePrice
Product group Antibodies
References
DNA ligase I antibody [C2C3], C-termGTX102936
ApplicationsWestern Blot
TargetLIG1
- SizePrice