DNA-PKcs antibody [18-2]
GTX21832
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetPRKDC
Overview
- SupplierGeneTex
- Product NameDNA-PKcs antibody [18-2]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID18-2
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID5591
- Target namePRKDC
- Target descriptionprotein kinase, DNA-activated, catalytic subunit
- Target synonymsDNA-dependent protein kinase catalytic subunit; DNAPK; DNA-PK catalytic subunit; DNAPKc; DNA-PKC; DNA-PKcs; DNPK1; hyper-radiosensitivity of murine scid mutation, complementing 1; HYRC; HYRC1; IMD26; p350; p460; protein kinase, DNA-activated, catalytic polypeptide; XRCC7
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
- ReactivityHuman, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 and c-Myc Activities. Sato H et al., 2015 Oct, J VirolRead more
- Non-homologous end joining pathway is the major route of protection against 4beta-hydroxywithanolide E-induced DNA damage in MCF-7 cells. You BJ et al., 2014 Mar, Food Chem ToxicolRead more
- Effect of DNA damage response by quinazolinone analogue HMJ-38 on human umbilical vein endothelial cells: evidence for gammaH2A.X and DNA-PK-dependent pathway. Chiang JH et al., 2014 Jun, Hum Exp ToxicolRead more