DNA-PKcs antibody [C3], C-term
GTX109673
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPRKDC
Overview
- SupplierGeneTex
- Product NameDNA-PKcs antibody [C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5591
- Target namePRKDC
- Target descriptionprotein kinase, DNA-activated, catalytic subunit
- Target synonymsDNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, S473K, XRCC7, p350, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, hyper-radiosensitivity of murine scid mutation, complementing 1, p460, protein kinase, DNA-activated, catalytic polypeptide, ser-473 kinase
- HostRabbit
- IsotypeIgG
- Protein IDP78527
- Protein NameDNA-dependent protein kinase catalytic subunit
- Scientific DescriptionThe PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Jang K, Park MJ, Park JS, et al. Computational inference of cancer-specific vulnerabilities in clinical samples. Genome Biol. 2020,21(1):155. doi: 10.1186/s13059-020-02077-1Read this paper



