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DNA polymerase gamma antibody

GTX100398
GeneTex
TargetPOLG
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    DNA polymerase gamma antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Concentration
    0.67 mg/ml
  • Formulation
    Liquid
  • Gene ID5428
  • Target name
    POLG
  • Target description
    DNA polymerase gamma, catalytic subunit
  • Target synonyms
    DNA polymerase subunit gamma-1; MDP1; MIRAS; mitochondrial DNA polymerase catalytic subunit; mitochondrial polymerase gamma catalytic subunit; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; PolG-alpha; polymerase (DNA directed), gamma; polymerase (DNA) gamma, catalytic subunit; SANDO; SCAE; truncated mitochondrial DNA polymerase gamma catalytic subunit; truncated mitochondrial polymerase gamma catalytic subunit
  • Protein IDP54098
  • Protein Name
    DNA polymerase subunit gamma-1
  • Scientific Description
    Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203