DNA polymerase gamma antibody [N1N2], N-term

GeneTex

DNA polymerase gamma antibody [N1N2], N-term

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

POLG

DNA polymerase gamma, catalytic subunit

MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE, DNA polymerase subunit gamma-1, 3'-5' exodeoxyribonuclease, 5'-deoxyribose-phosphate lyase, PolG-alpha, mitochondrial DNA polymerase catalytic subunit, mitochondrial polymerase gamma catalytic subunit, polymerase (DNA directed), gamma, polymerase (DNA) gamma, catalytic subunit

Rabbit

IgG

DNA polymerase subunit gamma-1

Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203