
Immunohistochemistry of paraffin-embedded mouse liver tissue using CSB-PA007083LA01HU at dilution of 1:100
DNMT3A Antibody
CSB-PA007083LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetDNMT3A
Overview
- SupplierCusabio
- Product NameDNMT3A Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1788
- Target nameDNMT3A
- Target descriptionDNA methyltransferase 3 alpha
- Target synonymscysteine methyltransferase DNMT3A; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA (cytosine-5)-methyltransferase 3A; DNA cytosine methyltransferase 3A2; DNA MTase HsaIIIA; DNMT3A2; HESJAS; M.HsaIIIA; TBRS
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6K1
- Protein NameDNA (cytosine-5)-methyltransferase 3A
- Scientific DescriptionRequired for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity
- Storage Instruction-20°C or -80°C
- UNSPSC12352203