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ProductsBack/DNMT3A Antibody

Immunohistochemistry of paraffin-embedded mouse liver tissue using CSB-PA007083LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded mouse liver tissue using CSB-PA007083LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded mouse liver tissue using CSB-PA007083LA01HU at dilution of 1:100

DNMT3A Antibody

CSB-PA007083LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetDNMT3A

Overview

Supplier
Cusabio
Product Name
DNMT3A Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID1788
Target name
DNMT3A
Target description
DNA methyltransferase 3 alpha
Target synonyms
cysteine methyltransferase DNMT3A; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA (cytosine-5)-methyltransferase 3A; DNA cytosine methyltransferase 3A2; DNA MTase HsaIIIA; DNMT3A2; HESJAS; M.HsaIIIA; TBRS
Host
Rabbit
Isotype
IgG
Protein IDQ9Y6K1
Protein Name
DNA (cytosine-5)-methyltransferase 3A
Scientific Description
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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