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DNMT3A antibody

GTX128157
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetDNMT3A
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Overview

  • Supplier
    GeneTex
  • Product Name
    DNMT3A antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.76 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1788
  • Target name
    DNMT3A
  • Target description
    DNA methyltransferase 3 alpha
  • Target synonyms
    DNMT3A2, HESJAS, M.HsaIIIA, TBRS, DNA (cytosine-5)-methyltransferase 3A, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA MTase HsaIIIA, DNA cytosine methyltransferase 3A2, cysteine methyltransferase DNMT3A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y6K1
  • Protein Name
    DNA (cytosine-5)-methyltransferase 3A
  • Scientific Description
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Tessier SN, Ingelson-Filpula WA, Storey KB. Epigenetic regulation by DNA methyltransferases during torpor in the thirteen-lined ground squirrel Ictidomys tridecemlineatus. Mol Cell Biochem. 2021,476(11):3975-3985. doi: 10.1007/s11010-021-04214-1
    Read this paper
  • Wijenayake S, Storey KB. The role of DNA methylation during anoxia tolerance in a freshwater turtle (Trachemys scripta elegans). J Comp Physiol B. 2016,186(3):333-42. doi: 10.1007/s00360-016-0960-x
    Read this paper