DNMT3A antibody
GTX128157
Overview
- SupplierGeneTex
- Product NameDNMT3A antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.76 mg/ml
- ConjugateUnconjugated
- Gene ID1788
- Target nameDNMT3A
- Target descriptionDNA methyltransferase 3 alpha
- Target synonymscysteine methyltransferase DNMT3A; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA (cytosine-5)-methyltransferase 3A; DNA cytosine methyltransferase 3A2; DNA MTase HsaIIIA; DNMT3A2; HESJAS; M.HsaIIIA; TBRS
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6K1
- Protein NameDNA (cytosine-5)-methyltransferase 3A
- Scientific DescriptionCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Epigenetic regulation by DNA methyltransferases during torpor in the thirteen-lined ground squirrel Ictidomys tridecemlineatus. Tessier SN et al., 2021 Nov, Mol Cell BiochemRead more
- The role of DNA methylation during anoxia tolerance in a freshwater turtle (Trachemys scripta elegans). Wijenayake S et al., 2016 Apr, J Comp Physiol BRead more