The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA189054(DNMT3L Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA189054(DNMT3L Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: x200)
DNMT3L Antibody
CSB-PA189054
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetDNMT3L
Overview
- SupplierCusabio
- Product NameDNMT3L Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID29947
- Target nameDNMT3L
- Target descriptionDNA methyltransferase 3 like
- Target synonymscytosine-5-methyltransferase 3-like protein; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; human cytosine-5-methyltransferase 3-like protein
- HostRabbit
- IsotypeIgG
- Protein IDQ9UJW3
- Protein NameDNA (cytosine-5)-methyltransferase 3-like
- Scientific DescriptionCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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