Dooku1

MedChem Express

Dooku1 [2253744-54-4]

10

2253744-54-4

99.93

C13H9Cl2N3OS

326.20

Dooku1 is a reversibly Yoda1 antagonist with IC 50 value of 1.3 microM and 1.5 microM for 2 microM Yoda1-induced Ca 2+ entry HEK 293 cells and HUVECs, respectively. Dooku1 can disrupt Yoda1-induced Piezo1 channel activity and inhibit Yoda1-induced relaxation of aorta. Dooku1 can be used for vascular physiology and disease research [1] .

ClC1=C(C(Cl)=CC=C1)CSC2=NN=C(C3=CC=CN3)O2

-20°C

12352200