Dooku1

AbMole BioScience

Dooku1

9

2253744-54-4

Chemical

Research Use Only

C13H9Cl2N3OS

326.2

Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibits 2 uM Yoda1-induced Ca2+Incoming, IC50 values in HEK 293 cells and HUVECs are 1.3 uM and 1.5 uM, respectively.

ClC1=C(CSC2=NN=C(O2)C3=CC=C[NH]3)C(=CC=C1)Cl

-20°C, dry, sealed

12352200