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DOPAL [5707-55-1]

DOPAL [5707-55-1]

T37533
TargetMol Chemicals
CAS Number5707-55-1
Product group Chemicals
Molecular Weight152.15
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    DOPAL [5707-55-1]
  • Delivery Days Customer
    44
  • CAS Number
    5707-55-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    DOPAL
  • Molecular Formula
    C8H8O3
  • Molecular Weight
    152.15
  • Scientific Description
    DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate alpha-synuclein, an event associated with Parkinsons disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL as well as neurodegeneration and motor dysfunction characteristic of Parkinsons disease.[4]
  • Shelf life instruction
    3 years
  • SMILES
    O=CCC1=CC=C(O)C(O)=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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