Doramapimod (BIRB 796) [285983-48-4]
S1574
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameDoramapimod (BIRB 796) [285983-48-4]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionDoramapimod (BIRB 796) is a pan-p38 MAPK inhibitor with IC50 of 38 nM, 65 nM, 200 nM and 520 nM for p38alfa/bèta/gamma/delta in cell-free assays, and binds p38alfa with Kd of 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2.
- UNSPSC12352200
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CAS Number285983-48-4
Estimated Purity0.99
Molecular Weight527.66
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![Doramapimod [285983-48-4]](https://www.targetmol.com/group3/M00/35/47/CgoaEGayGqOEYeypAAAAAKTDVcU071.png)
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Estimated Purity99.65%
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Molecular Weight527.7 Da
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Estimated Purity99.98
Molecular Weight527.66
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