ProductsBack/DR4 antibody [DR-4-02] (PE)

FACS analysis of CD261-transfected HEK-293 cells using GTX80184 DR4 antibody [DR-4-02] (PE).

DR4 antibody [DR-4-02] (PE)

Name: DR4 antibody [DR-4-02] (PE)
SKU: GTX80184_G10
Availability: BackOrder

GTX80184

TargetTNFRSF10A

Product group Antibodies

Overview

Supplier
GeneTex
Product Name
DR4 antibody [DR-4-02] (PE) - Overexpression Validated
Delivery Days Customer
9
Clone ID
DR-4-02
Concentration
0.1 mg/ml
Formulation
Liquid
Gene ID8797
Target name
TNFRSF10A
Target description
TNF receptor superfamily member 10a
Target synonyms
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a
Protein IDO00220
Protein Name
Tumor necrosis factor receptor superfamily member 10A
Scientific Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Storage Instruction
2°C to 8°C
UNSPSC
12352203

Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile. Yagolovich AV et al., 2020 Apr, Transl Oncol
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