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ProductsBack/DR4 antibody [DR-4-02] (FITC)
FACS analysis of CD261-transfected HEK-293 cells using GTX80183 DR4 antibody [DR-4-02] (FITC).
FACS analysis of CD261-transfected HEK-293 cells using GTX80183 DR4 antibody [DR-4-02] (FITC).
FACS analysis of CD261-transfected HEK-293 cells using GTX80183 DR4 antibody [DR-4-02] (FITC).

DR4 antibody [DR-4-02] (FITC)

GTX80183
GeneTex
ApplicationsFlow Cytometry
DownloadDatasheet
Product group Antibodies
TargetTNFRSF10A
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Overview

  • Supplier
    GeneTex
  • Product Name
    DR4 antibody [DR-4-02] (FITC) - Overexpression Validated
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    DR-4-02
  • Concentration
    0.1 mg/ml
  • Conjugate
    FITC
  • Gene ID8797
  • Target name
    TNFRSF10A
  • Target description
    TNF receptor superfamily member 10a
  • Target synonyms
    APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDO00220
  • Protein Name
    Tumor necrosis factor receptor superfamily member 10A
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile. Yagolovich AV et al., 2020 Apr, Transl Oncol
    Read more

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