Bio-Connect

DR5 antibody

Research Use Only
GTX70465
GeneTex
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetTNFRSF10B
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Overview

  • Supplier
    GeneTex
  • Product Name
    DR5 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Reacts with the N terminus of the human TRAIL-R2 protein.
  • Application Supplier Note
    Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID8795
  • Target name
    TNFRSF10B
  • Target description
    TNF receptor superfamily member 10b
  • Target synonyms
    apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; DR5; Fas-like protein; KILLER; KILLER/DR5; p53-regulated DNA damage-inducible cell death receptor(killer); TNF-related apoptosis-inducing ligand receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; ZTNFR9
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO14763
  • Protein Name
    Tumor necrosis factor receptor superfamily member 10B
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203