DRI-C21045

AbMole BioScience

DRI-C21045

9

2101765-81-3

Research Use Only

C32H24N2O7S

580.61

DRI-C21045 is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 uM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-kappaB and B cell proliferation all induced by CD40L with IC50s of 17.1 uM and 4.5 uM, respectively.

12352200