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ICC/IF analysis of HeLa cells using GTX09511 Drosha antibody [GT1178]. Orange: Primary antibody Blue: DAPI
ICC/IF analysis of HeLa cells using GTX09511 Drosha antibody [GT1178]. Orange: Primary antibody Blue: DAPI
ICC/IF analysis of HeLa cells using GTX09511 Drosha antibody [GT1178]. Orange: Primary antibody Blue: DAPI

Drosha antibody [GT1178]

GTX09511
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetDROSHA
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Overview

  • Supplier
    GeneTex
  • Product Name
    Drosha antibody [GT1178]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT1178
  • Conjugate
    Unconjugated
  • Gene ID29102
  • Target name
    DROSHA
  • Target description
    drosha ribonuclease III
  • Target synonyms
    drosha, double-stranded RNA-specific endoribonuclease; ETOHI2; HSA242976; nuclear RNase III Drosha; p241; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; RANSE3L; ribonuclease 3; ribonuclease type III, nuclear; RN3; RNase III; RNASE3L; RNASEN
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NRR4
  • Protein Name
    Ribonuclease 3
  • Scientific Description
    This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a hmuan cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in hmuan patients with kidney cancer. [provided by RefSeq, Sep 2016]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203