DS-1205 [1855860-24-0]

TargetMol Chemicals

DS-1205 [1855860-24-0]

9

1855860-24-0

Chemical

Research Use Only

DS-1205

99.28%

C41H42FN5O7

735.8

DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205 also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205 can inhibit cell migration in vitro and tumor growth in vivo[1].

3 years

COc1cc(ccc1OC[C@H]1COCCO1)-c1cnc(N)c(c1)-c1ccc(NC(=O)c2cn(CC3CCOCC3)cc(-c3ccc(C)cn3)c2=O)cc1F

-20°C

12352200