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DTHIB

ORB1089349
Biorbyt
CAS Number897326-30-6
Product group Chemicals
Molecular Weight309.68
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Overview

  • Supplier
    Biorbyt
  • Product Name
    DTHIB [897326-30-6]
  • Delivery Days Customer
    10
  • CAS Number
    897326-30-6
  • Certification
    Research Use Only
  • Molecular Formula
    C13H9ClFN3O3
  • Molecular Weight
    309.68
  • Scientific Description
    DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB inhibits HSF1 cancer gene signature (HSF1 CaSig) and selectively stimulates degradation of nuclear HSF1. DTHIB has potently anticancer activities and can be used for prostate cancer research.
  • SMILES
    O=C(NC1=CC=C(F)C=C1)NC2=CC=C(Cl)C([N+]([O-])=O)=C2
  • UNSPSC
    12352200

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