DXO Antibody, HRP conjugated

Cusabio

DXO Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

DXO

decapping exoribonuclease

5'-3' exoribonuclease DXO; decapping and exoribonuclease protein; deNADding enzyme DXO; DOM3L; DOM3Z; NAD-capped RNA hydrolase DXO; NG6; protein Dom3Z; RAI1

Rabbit

IgG

Decapping and exoribonuclease protein

Ribonuclease that specifically degrades pre-mRNAs with a defective 5 end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5-3 exonuclease activities. Has decapping activity toward incomplete 5 end cap mRNAs such as unmethylated 5 end-capped RNA to release GpppN and 5 end monophosphate RNA. The 5 end monophosphate RNA is then degraded by the 5-3 exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5-pyrophosphohydrolase activity by hydrolyzing the 5 end triphosphate to release pyrophosphates (By similarity).

Human

-20°C or -80°C

12352203