Ebselen [60940-34-3]

MedChem Express

Ebselen [60940-34-3]

10

60940-34-3

Research Use Only

99.58

C13H9NOSe

274.181

Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker[1][2]. Ebselen potently inhibits Mpro (IC50=0.67 microM) and COVID-19 virus (EC50=4.67 microM)[3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity[4][5].

O=C1N(C2=CC=CC=C2)[Se]C3=C1C=CC=C3

-20°C,2°C to 8°C

12352200