Ebselen [60940-34-3]
T0825
Overview
- SupplierTargetMol Chemicals
- Product NameEbselen [60940-34-3]
- Delivery Days Customer4
- CAS Number60940-34-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameEbselen
- Estimated Purity99.38%
- Molecular FormulaC13H9NOSe
- Molecular Weight274.18
- Scientific DescriptionEbselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.
- Shelf life instruction3 years
- SMILESO=C1N([Se]C=2C1=CC=CC2)C3=CC=CC=C3
- Storage Instruction-20°C
- UNSPSC12352200
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