WB analysis of various samples using GTX00902 EDD antibody. Lane 1 : HeLa cells transfected with control siRNA Lane 2 : HeLa cells transfected with EDD-specific siRNA Lane 3 : HEK293T cells transfected with pFlag-CMV-5b empty vector Lane 4 : HEK293T cells transfected with pCMV-Tag2b-EDD expression vector
WB analysis of various samples using GTX00902 EDD antibody. Lane 1 : HeLa cells transfected with control siRNA Lane 2 : HeLa cells transfected with EDD-specific siRNA Lane 3 : HEK293T cells transfected with pFlag-CMV-5b empty vector Lane 4 : HEK293T cells transfected with pCMV-Tag2b-EDD expression vector
EDD antibody - KO/KD Validated
GTX00902
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetUBR5
Overview
- SupplierGeneTex
- Product NameEDD antibody - KO/KD Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID51366
- Target nameUBR5
- Target descriptionubiquitin protein ligase E3 component n-recognin 5
- Target synonymsDD5; E3 identified by differential display; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase, HECT domain-containing 1; EDD; EDD1; HECT-type E3 ubiquitin transferase UBR5; HYD; hyperplastic discs protein homolog; progestin-induced protein
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203