Edoxaban

MedChem Express

Edoxaban [480449-70-5]

10

480449-70-5

Research Use Only

99.81

C24H30ClN7O4S

548.06

Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with K i values of 0.561 and 2.98 nM for free human FXa and prothrombinase . Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research [1] .

O=C(N(C)C)[C@@H](CC1)C[C@H]([C@H]1NC(C(NC(C=C2)=NC=C2Cl)=O)=O)NC(C3=NC(CC4)=C(CN4C)S3)=O

-20°C,2°C to 8°C

12352200