Edoxaban [480449-70-5]

TargetMol Chemicals

Edoxaban [480449-70-5]

9

480449-70-5

Chemical

Research Use Only

Edoxaban

99.71%

C24H30ClN7O4S

548.06

Edoxaban (Lixiana) (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and is able to be used for stroke prevention. Edoxaban is a also weak inhibitor of thrombin and factor IXabeta (FIXa), with K i s of 6.00 microM and 41.7 microM, respectively, exhibits >10 000-fold selectivity for FXa. Edoxaban has antithrombotic properties and is potential for thromboembolic diseases treatment [1] [2] [3].

3 years

N(C(=O)C1=NC2=C(S1)CN(C)CC2)[C@H]3[C@@H](NC(C(NC4=CC=C(Cl)C=N4)=O)=O)CC[C@H](C(N(C)C)=O)C3

-20°C

12352200