Western blot All lanes: Polycomb protein EED antibody at 4ug/ml Lane 1: Hela whole cell lysate Lane 2: K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 51, 54, 46 kDa Observed band size: 51 kDa
Western blot All lanes: Polycomb protein EED antibody at 4ug/ml Lane 1: Hela whole cell lysate Lane 2: K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 51, 54, 46 kDa Observed band size: 51 kDa
EED Antibody
CSB-PA007408ESR1HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetEED
Overview
- SupplierCusabio
- Product NameEED Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8726
- Target nameEED
- Target descriptionembryonic ectoderm development
- Target synonymsCOGIS; embryonic ectoderm development protein; HEED; polycomb protein EED; WAIT1; WD protein associating with integrin cytoplasmic tails 1
- HostRabbit
- IsotypeIgG
- Protein IDO75530
- Protein NamePolycomb protein EED
- Scientific DescriptionPolycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates Lys-9 and Lys-27 of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes Lys-26 trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 Lys-27, whereas H3 Lys-27 recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203