EGFR (phospho Tyr1068) antibody
GTX132810
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetEGFR
Overview
- SupplierGeneTex
- Product NameEGFR (phospho Tyr1068) antibody
- Delivery Days Customer9
- Antibody SpecificityThe full-length EGFR includes the 24 aa signal peptide that is cleaved during EGFR maturation. The Tyr1068 of mature EGFR is equivalent to Tyr1092 of uncleaved EGFR.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.09 mg/ml
- ConjugateUnconjugated
- Gene ID1956
- Target nameEGFR
- Target descriptionepidermal growth factor receptor
- Target synonymsavian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Targeting the Axl and mTOR Pathway Synergizes Immunotherapy and Chemotherapy to Butylidenephthalide in a Recurrent GBM. Liu CA et al., 2022, J OncolRead more
- PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer LettRead more
- Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Li J et al., 2020 Jul 15, J EthnopharmacolRead more
- The novel application of cordycepin in maintaining stem cell pluripotency and increasing iPS cell generation efficiency. Wang CH et al., 2020 Feb 10, Sci RepRead more
- EGFR/ErbB Inhibition Promotes OPC Maturation up to Axon Engagement by Co-Regulating PIP2 and MBP. Nocita E et al., 2019 Aug 6, CellsRead more
- Sodium thiosulfate enhances production of polysaccharides and anticancer activities of sulfated polysaccharides in Antrodia cinnamomea. Lin TY et al., 2019 Jul 15, Carbohydr PolymRead more
- EGFR transactivation is involved in TNF-alpha-induced expression of thymic stromal lymphopoietin in human keratinocyte cell line. Segawa R et al., 2018 Mar, J Dermatol SciRead more