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ProductsBack/EGFR-pS671 Polyclonal Antibody AE00301
Formaldehyde-fixed, paraffin-embedded human pituitary carcinoma stained with EGFR-pS671 Rabbit Polyclonal Antibody AE00301 at 10ug/ml for 1.5h at ambient temperature. Epitope retrieval: Pressure cooker heating at pH6 for 3min, then cool by running cold water for 10min. DAB staining by HRP.
Formaldehyde-fixed, paraffin-embedded human pituitary carcinoma stained with EGFR-pS671 Rabbit Polyclonal Antibody AE00301 at 10ug/ml for 1.5h at ambient temperature. Epitope retrieval: Pressure cooker heating at pH6 for 3min, then cool by running cold water for 10min. DAB staining by HRP.
Formaldehyde-fixed, paraffin-embedded human pituitary carcinoma stained with EGFR-pS671 Rabbit Polyclonal Antibody AE00301 at 10ug/ml for 1.5h at ambient temperature. Epitope retrieval: Pressure cooker heating at pH6 for 3min, then cool by running cold water for 10min. DAB staining by HRP.

EGFR-pS671 Polyclonal Antibody AE00301

Research Use Only
AE00301
Aeonian Biotech
ApplicationsWestern Blot, ImmunoHistoChemistry
DownloadDatasheet
DownloadMSDS
Product group Antibodies
ReactivityHuman
TargetEGFR
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Overview

  • Supplier
    Aeonian Biotech
  • Product Name
    EGFR-pS671 Polyclonal Antibody
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Applications Supplier
    IHC, WB
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1956
  • Target name
    EGFR
  • Target description
    epidermal growth factor receptor
  • Target synonyms
    avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Protein IDP00533
  • Protein Name
    Epidermal growth factor receptor
  • Scientific Description
    EGFR-pS671 Polyclonal Antibody AE00301
  • Shelf life instruction
    Integrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
  • Reactivity
    Human
  • Reactivity Supplier
    Human, Mouse, Rat
  • Storage Instruction
    2-8°C
  • UNSPSC
    12352203

References

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    Read more
  • Blombery P, Lew TE, Dengler MA, Thompson ER, Lin VS, Chen X, Nguyen T, Panigrahi A, Handunnetti SM, Carney D, Westerman DA, Tam CS, Adams JM, Wei AH, Huang DCS, Seymour JF, Roberts A, Anderson MA. Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL. Blood. 2021 Sep 1:blood.2021012775. doi: 10.1182/blood.2021012775. PMID: 34469514.
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  • Seiller C, Maiga S, Touzeau C, Bellanger C, Kervoëlen C, Descamps G, Maillet L, Moreau P, Pellat-Deceunynck C, Gomez-Bougie P, Amiot M. Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/BAK hetero-complexes. Cell Death Dis. 2020 May 5;11(5):316. doi: 10.1038/s41419-020-2505-1. PMID: 32371863.
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  • Wang TS, Coppens I, Saorin A, Brady NR, Hamacher-Brady A. Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling. Dev Cell. 2020 Jun 22;53(6):627-645.e7. doi: 10.1016/j.devcel.2020.05.014. PMID: 32504557.
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  • Lindenboim L, Grozki D, Amsalem-Zafran AR, Peña-Blanco A, Gundersen GG, Borner C, Hodzic D, Garcia-Sáez AJ, Worman HJ, Stein R. Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins. Cell Death Discov. 2020 Sep 18;6(1):90. doi: 10.1038/s41420-020-00327-6. PMID: 34535629.
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