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Formaldehyde-fixed, paraffin-embedded human colon carcinoma stained with EGFR-pT669 Rabbit Polyclonal Antibody AE00299 at 5ug/ml for 1.5h at ambient temperature. Epitope retrieval: Pressure cooker heating at pH6 for 3min, then cool by running cold water for 10min. DAB staining by HRP.
Formaldehyde-fixed, paraffin-embedded human colon carcinoma stained with EGFR-pT669 Rabbit Polyclonal Antibody AE00299 at 5ug/ml for 1.5h at ambient temperature. Epitope retrieval: Pressure cooker heating at pH6 for 3min, then cool by running cold water for 10min. DAB staining by HRP.
Formaldehyde-fixed, paraffin-embedded human colon carcinoma stained with EGFR-pT669 Rabbit Polyclonal Antibody AE00299 at 5ug/ml for 1.5h at ambient temperature. Epitope retrieval: Pressure cooker heating at pH6 for 3min, then cool by running cold water for 10min. DAB staining by HRP.

EGFR-pT669 Polyclonal Antibody AE00299

Research Use Only
AE00299
Aeonian Biotech
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetEGFR
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Overview

  • Supplier
    Aeonian Biotech
  • Product Name
    EGFR-pT669 Polyclonal Antibody
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Applications Supplier
    IHC, WB
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1956
  • Target name
    EGFR
  • Target description
    epidermal growth factor receptor
  • Target synonyms
    avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Protein IDP00533
  • Protein Name
    Epidermal growth factor receptor
  • Scientific Description
    EGFR-pT669 Polyclonal Antibody AE00299
  • Shelf life instruction
    Integrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
  • Reactivity
    Human
  • Reactivity Supplier
    Human, Mouse, Rat
  • Storage Instruction
    2-8°C
  • UNSPSC
    12352203

References

  • Masemann D, Meissner R, Schied T, Lichty BD, Rapp UR, Wixler V, Ludwig S. Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers. Oncoimmunology. 2021 Feb 17;10(1):1885778. doi: 10.1080/2162402X.2021.1885778. PMID: 33643696.
    Read more
  • Cheng N, Bei Y, Song Y, Zhang W, Xu L, Zhang W, Yang N, Bai X, Shu Y, Shen P. B7-H3 augments the pro-angiogenic function of tumor-associated macrophages and acts as a novel adjuvant target for triple-negative breast cancer therapy. Biochem Pharmacol. 2021 Jan;183:114298. doi: 10.1016/j.bcp.2020.114298. Epub 2020 Oct 22. PMID: 33153969.
    Read more
  • Mao L, Fan TF, Wu L, Yu GT, Deng WW, Chen L, Bu LL, Ma SR, Liu B, Bian Y, Kulkarni AB, Zhang WF, Sun ZJ. Selective blockade of B7-H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma. J Cell Mol Med. 2017 Sep;21(9):2199-2210. doi: 10.1111/jcmm.13143. PMID: 28401653.
    Read more