Formaldehyde-fixed, paraffin-embedded human colon carcinoma stained with EGFR-pT669 Rabbit Polyclonal Antibody AE00299 at 5ug/ml for 1.5h at ambient temperature. Epitope retrieval: Pressure cooker heating at pH6 for 3min, then cool by running cold water for 10min. DAB staining by HRP.
EGFR-pT669 Polyclonal Antibody AE00299
AE00299
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetEGFR
Overview
- SupplierAeonian Biotech
- Product NameEGFR-pT669 Polyclonal Antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry
- Applications SupplierIHC, WB
- Category SupplierAntibody
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1956
- Target nameEGFR
- Target descriptionepidermal growth factor receptor
- Target synonymsavian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Protein IDP00533
- Protein NameEpidermal growth factor receptor
- Scientific DescriptionEGFR-pT669 Polyclonal Antibody AE00299
- Shelf life instructionIntegrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
- ReactivityHuman
- Reactivity SupplierHuman, Mouse, Rat
- Storage Instruction2-8°C
- UNSPSC12352203
References
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- Cheng N, Bei Y, Song Y, Zhang W, Xu L, Zhang W, Yang N, Bai X, Shu Y, Shen P. B7-H3 augments the pro-angiogenic function of tumor-associated macrophages and acts as a novel adjuvant target for triple-negative breast cancer therapy. Biochem Pharmacol. 2021 Jan;183:114298. doi: 10.1016/j.bcp.2020.114298. Epub 2020 Oct 22. PMID: 33153969.Read more
- Mao L, Fan TF, Wu L, Yu GT, Deng WW, Chen L, Bu LL, Ma SR, Liu B, Bian Y, Kulkarni AB, Zhang WF, Sun ZJ. Selective blockade of B7-H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma. J Cell Mol Med. 2017 Sep;21(9):2199-2210. doi: 10.1111/jcmm.13143. PMID: 28401653.Read more