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ProductsBack/EGLN1 Polyclonal Antibody

Immunofluorescence analysis of MCF-7 cells using EGLN1 Polyclonal Antibody

Immunofluorescence analysis of MCF-7 cells using EGLN1 Polyclonal Antibody

Immunofluorescence analysis of MCF-7 cells using EGLN1 Polyclonal Antibody

EGLN1 Polyclonal Antibody

E-AB-65402

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
EGLN1 Polyclonal Antibody
Delivery Days Customer
12
Certification
Research Use Only
Scientific Description
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
UNSPSC
12352203

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