
WB analysis of mouse liver(lane 1), kidney(lane 2) tissue lysate (35ug/lane) using GTX81126 EHHADH antibody, C-term.
EHHADH antibody, C-term
GTX81126
Overview
- SupplierGeneTex
- Product NameEHHADH antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID1962
- Target nameEHHADH
- Target descriptionenoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
- Target synonyms3,2-trans-enoyl-CoA isomerase; ECHD; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; FRTS3; L-3-hydroxyacyl-CoA dehydrogenase; LBFP; L-bifunctional protein, peroxisomal; LBP; L-PBE; MFE1; multifunctional enzyme 1; PBE; PBFE; peroxisomal bifunctional enzyme; peroxisomal enoyl-CoA hydratase
- Protein IDQ08426
- Protein NamePeroxisomal bifunctional enzyme
- Scientific DescriptionThe protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice. Ranea-Robles P et al., 2021 Sep, Kidney360Read more
- The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis. Ranea-Robles P et al., 2021 Nov, J Inherit Metab DisRead more
- Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis. Ranea-Robles P et al., 2021 Jul, Cell Mol Life SciRead more
- Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4. Violante S et al., 2019 Mar, FASEB JRead more