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WB analysis of mouse liver(lane 1), kidney(lane 2) tissue lysate (35ug/lane) using GTX81126 EHHADH antibody, C-term.
WB analysis of mouse liver(lane 1), kidney(lane 2) tissue lysate (35ug/lane) using GTX81126 EHHADH antibody, C-term.
WB analysis of mouse liver(lane 1), kidney(lane 2) tissue lysate (35ug/lane) using GTX81126 EHHADH antibody, C-term.

EHHADH antibody, C-term

GTX81126
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetEHHADH
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Overview

  • Supplier
    GeneTex
  • Product Name
    EHHADH antibody, C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1962
  • Target name
    EHHADH
  • Target description
    enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
  • Target synonyms
    3,2-trans-enoyl-CoA isomerase; ECHD; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; FRTS3; L-3-hydroxyacyl-CoA dehydrogenase; LBFP; L-bifunctional protein, peroxisomal; LBP; L-PBE; MFE1; multifunctional enzyme 1; PBE; PBFE; peroxisomal bifunctional enzyme; peroxisomal enoyl-CoA hydratase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ08426
  • Protein Name
    Peroxisomal bifunctional enzyme
  • Scientific Description
    The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice. Ranea-Robles P et al., 2021 Sep, Kidney360
    Read more
  • The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis. Ranea-Robles P et al., 2021 Nov, J Inherit Metab Dis
    Read more
  • Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis. Ranea-Robles P et al., 2021 Jul, Cell Mol Life Sci
    Read more
  • Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4. Violante S et al., 2019 Mar, FASEB J
    Read more

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