
WB analysis of mouse liver(lane 1), kidney(lane 2) tissue lysate (35ug/lane) using GTX81126 EHHADH antibody, C-term.
EHHADH antibody, C-term
GTX81126
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetEHHADH
Overview
- SupplierGeneTex
- Product NameEHHADH antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1962
- Target nameEHHADH
- Target descriptionenoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
- Target synonymsECHD, FRTS3, L-PBE, LBFP, LBP, MFE1, PBFE, peroxisomal bifunctional enzyme, 3,2-trans-enoyl-CoA isomerase, L-3-hydroxyacyl-CoA dehydrogenase, L-bifunctional protein, peroxisomal, PBE, enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase, enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase, multifunctional enzyme 1, peroxisomal enoyl-CoA hydratase
- HostRabbit
- IsotypeIgG
- Protein IDQ08426
- Protein NamePeroxisomal bifunctional enzyme
- Scientific DescriptionThe protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ranea-Robles P, Portman K, Bender A, et al. Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice. Kidney360. 2021,2(9):1441-1454. doi: 10.34067/KID.0003772021Read this paper
- Ranea-Robles P, Chen H, Stauffer B, et al. The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis. J Inherit Metab Dis. 2021,44(6):1419-1433. doi: 10.1002/jimd.12440Read this paper
- Ranea-Robles P, Violante S, Argmann C, et al. Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis. Cell Mol Life Sci. 2021,78(14):5631-5646. doi: 10.1007/s00018-021-03869-9Read this paper
- Violante S, Achetib N, van Roermund CWT, et al. Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4. FASEB J. 2019,33(3):4355-4364. doi: 10.1096/fj.201801498RRead this paper








