EHT 1864 2HCl

AbMole BioScience

EHT 1864 2HCl

9

754240-09-0

Chemical

Research Use Only

C25H27F3N2O4S.2HCl

581.47

EHT 1864 is a potent inhibitor of Rac family GTPases. EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The Kd values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.

Cl.Cl.FC(F)(F)C1=CC2=C(C=C1)C(=CC=N2)SCCCCCOC3=COC(=CC3=O)CN4CCOCC4

12352200