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EIF2 beta antibody

GTX106484
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetEIF2S2
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Overview

  • Supplier
    GeneTex
  • Product Name
    EIF2 beta antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8894
  • Target name
    EIF2S2
  • Target description
    eukaryotic translation initiation factor 2 subunit beta
  • Target synonyms
    EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta, eukaryotic translation initiation factor 2 subunit 2, eIF2-beta, eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa, protein phosphatase 1, regulatory subunit 67
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP20042
  • Protein Name
    Eukaryotic translation initiation factor 2 subunit 2
  • Scientific Description
    Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012
    Read this paper
  • Rossi S, Serrano A, Gerbino V, et al. Nuclear accumulation of mRNAs underlies G4C2-repeat-induced translational repression in a cellular model of C9orf72 ALS. J Cell Sci. 2015,128(9):1787-99. doi: 10.1242/jcs.165332
    Read this paper
  • Knight JR, Bastide A, Roobol A, et al. Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation. Biochem J. 2015,465(2):227-38. doi: 10.1042/BJ20141014
    Read this paper

Datasheet

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