EIF3 beta antibody [N2C3]

GeneTex

EIF3 beta antibody [N2C3]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

2 mg/ml

Unconjugated

EIF3I

eukaryotic translation initiation factor 3 subunit I

eIF3-beta; eIF3-p36; EIF3S2; eukaryotic translation initiation factor 3 subunit 2; eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; predicted protein of HQ2242; PRO2242; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP1; TRIP-1

Rabbit

IgG

Eukaryotic translation initiation factor 3 subunit I

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Human

-20°C or -80°C,2°C to 8°C

12352203