eIF3H / EIF3S3 antibody [N2C3]

GeneTex

eIF3H / EIF3S3 antibody [N2C3]

9

Western Blot

Research Use Only

Polyclonal

0.87 mg/ml

Unconjugated

EIF3H

eukaryotic translation initiation factor 3 subunit H

eIF3 p40 subunit; eIF-3-gamma; eIF3-gamma; eIF3-p40; EIF3S3; eukaryotic translation initiation factor 3 subunit 3; eukaryotic translation initiation factor 3 subunit H; eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD); eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa

Rabbit

IgG

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Human

2°C to 8°C,-20°C or -80°C

12352203