EMI1 antibody [EMI1/1176]

GeneTex

EMI1 antibody [EMI1/1176]

9

WB: 1-2microg/ml for 60 minutes at RT. IHC-P: 1-2microg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Monoclonal

EMI1/1176

0.2 mg/ml

Unconjugated

FBXO5

F-box protein 5

early mitotic inhibitor 1; EMI1; F-box only protein 5; F-box protein Fbx5; FBX5; Fbxo31

Mouse

IgG2a

F-box only protein 5

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203