EN460

MedChem Express

EN460 [496807-64-8]

10

496807-64-8

Research Use Only

99.73

C22H12ClF3N2O4

460.79

EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 ( IC 50 of 1.9 microM) interacts selectively with the reduced, active form of ERO1alpha and prevents its reoxidation [1] .

FC(F)(F)C1=NN(C2=CC(C(O)=O)=C(Cl)C=C2)C(/C1=C\C3=CC=C(C4=CC=CC=C4)O3)=O

-20°C,2°C to 8°C

12352200